The Company:

This publicly held clinical-stage biotechnology company is focused on developing treatments for patients suffering from complex rare diseases using its novel cell penetrating peptide technology platform. Their lead product candidate, CTI-1601, is a subcutaneously administered, recombinant fusion protein intended to deliver human frataxin (FXN), an essential protein to the mitochondria of patients with Friedreich’s ataxia. Friedreich’s ataxia is a rare, progressive, and fatal disease in which patients are unable to produce sufficient FXN due to a genetic abnormality. 

The company has assembled an experienced management team, each of whom has over 20 years of pharmaceutical industry experience and has about 45 employees. Their management team, employees, and consultants have significant expertise in discovery, nonclinical and clinical development, regulatory affairs and the development of manufacturing processes utilizing good manufacturing practices (GMPs). 

The company’s strategy is to become a leader in the treatment of rare diseases by leveraging their technology platform and applying their team’s know-how and expertise to the development of CTI-1601 and other future pipeline programs. They are best characterized by entrepreneurial and scientific leadership and a participatory workforce committed to success.

Position Summary:

We are seeking for our Philadelphia-based R&D laboratory a creative, motivated Research Associate/Scientist with expertise in cell biology laboratory techniques to contribute to the development of our novel, cell-penetrating peptide-based platform for biologics delivery. As a member of the Discovery team, you’ll directly participate in all steps of preclinical R&D from target validation and mechanism of action studies to the design and management of IND-enabling studies.

This role requires a BA/BS with at least 5 years of experience or MS with at least 2 years of relevant research experience in molecular biology, cell biology, or a related life science discipline.  Prior experience in the biotech/pharmaceutical industry is preferred, as is experience in mitochondrial biology, protein degradation, and/or neurodegeneration.

This role requires a BA/BS (Associate Scientist) or MS (Research Scientist) with at least 3 years of experience in molecular biology, cell biology, or a related life science research. Candidates with prior experience in biotech or at a CRO are especially encouraged to apply.

The successful candidate will have:

• A demonstrated proficiency in diverse cell biology and biochemistry techniques such as: mammalian cell culture, protein analysis and quantification, microscopy, gene expression analysis, and/or cell-based assays
• The ability to communicate and collaborate effectively with other members of the discovery team in a fast-paced environment 
• Excellent problem-solving skills
• The ability to adapt to changing priorities and deadlines
• Excellent planning, organization and time management skills including the ability to support and prioritize multiple projects
• Strong interpersonal communication skills, with the ability to effectively communicate the needs of the company’s programs to external collaborators as well as different stakeholders within the company