Manufacturing Operator

Lyra Therapeutics, Inc. is a clinical-stage biotechnology company developing novel, integrated drug and delivery solutions for the localized treatment of patients with chronic rhinosinusitis (CRS) and other chronic diseases. Lyra has two investigational product candidates, LYR-210 and LYR-220, in late-stage development for CRS, a highly prevalent inflammatory disease of the paranasal sinuses which leads to debilitating symptoms and significant morbidities. LYR-210 and LYR-220 are bioresorbable polymeric matrices designed to be administered in a brief, non-invasive, in-office procedure and are intended to deliver up to six months of continuous mometasone furoate drug therapy to the sinonasal passages as an alternative to sinus surgery. LYR-210 is designed for surgically naïve patients and is being evaluated in the ENLIGHTEN Phase 3 clinical program, while LYR-220, an enlarged matrix, is being evaluated in patients who have recurrent symptoms despite surgery in the BEACON Phase 2 clinical trial.  These two product candidates are designed to treat the estimated four million CRS patients in the United States who fail medical management each year. 

Our team is growing and we are currently seeking a Manufacturing Operator to support production of drug products.  The ideal candidate will be adaptable and motivated by the opportunity to learn new technologies and have proven success in a dynamic and fast-paced environment.


  • Manufacture drug products in Cleanroom environment
  • Follow all relevant SOPs, work instructions, batch records, and other controlling documentation when performing activities
  • Prepare solutions for chemical processes
  • Perform solution spray-coating experiments
  • Perform preparation and inspection activities under a microscope
  • Perform routine testing to produce reliable and precise data to support product development while following strict methodology
  • Assist in the collection and analysis of test data 
  • Maintain appropriate lab notebook and other records in accordance with GDP, GMP, and Lyra standards

At Lyra, we value creativity, leadership, and collaboration.  The company sees significant expansion opportunities for our platform, and look for people who are driven to succeed, innovative, and adaptable.  We offer a competitive compensation and benefit package with opportunities to join a fast-paced, high performing team.  For consideration, please submit cover letter and CV.

Please visit for more information.  



•  High School diploma/GED or Associate’s Degree in Science or Engineering

•  2+ years of related industrial experience in medical device or biotech manufacturing

•  Experience with polymeric spray coatings and working knowledge of spray coating technology is a plus

•  Proficient with basic lab skills and lab equipment with the ability to safely work with chemicals and solvents

•  Work under the direction of engineers and technicians with minimal supervision.  Ability to take direction, work independently, manage time, and effectively interact with various groups and personnel

•  Ability to adhere to GDP/GMP practices

•  Solid skills in Microsoft Office (Word, Excel, PowerPoint) 

•  Demonstrated commitment to safety

•  Available to work 40+ hours per week; weekly schedule may change per project demands