Job Type

Title: Scientist

Marengo Therapeutics, a clinical-stage biotech company, is pioneering first-in-class therapeutics that activate the right immune response to promote lifelong protection against cancer. Marengo has uncovered a novel approach to T cell activation by targeting Vß TCR chain to unleash rapid, potent, and long-lasting anti-tumor immune responses in a safe and effective way. We’re leveraging our versatile, proprietary bispecific fusion protein platform to selectively deliver the right activation to the right T cell subsets, customizable to patient needs with its tunable properties, with an initial focus on advanced solid tumors and broad applicability beyond.

Marengo is driven by core values that guide our company’s mission and approach from the inside out: we demonstrate an unparalleled commitment to patients and their loved ones, we are confident in our science and our team, we operate with courage, and we creatively apply deep expertise to new ways of thinking with curiosity and imagination. With an exciting journey ahead and a tremendous opportunity for growth, now is the time to join the Marengo team and make an impact on cancer patient care – are you ready to join the new frontier?

Role: Marengo is seeking a lab/bench scientist with immunology experience in developing and performing cell-based assays using human, NHP, and rodent immune cells to determine the extent of target engagement and validation in the area of bispecific antibody modalities to assess target cell depletion, immune cell activation and phenotyping and cell cytoxicity. Proficiency with FlowJo, Prism, and Microsoft Office applications is desired.

Who are we looking for? 

· You are an energetic and passionate scientist who likes to think outside of the box, challenge the norm, and is passionate about the company’s mission of discovering and developing new medications

· You are a resourceful self-starter and team player with a strong results orientation

· You consider yourself a guru in lab technologies and research techniques

· You can develop trusting relationships to gain support and achieve results at all levels of the organization

What are we looking for?

· A driven professional who knows how to work and contribute to an ever-changing working environment

· A collegial individual who enjoys working in close collaboration with peers in the research, development, and administrative areas of the company

· A willingness to learn new things, adapt to new ways, and go with the flow

· A person who thrives in a small company atmosphere

· Ability to determine task priority and maintain established deadlines

What are we offering?

· Membership within a growing, CARING, and collegial organization

· Being part of a passionate, involved, and cutting-edge Research Team

· Exposure to pioneering science and the discovery of drugs to help treat patients


· Contribute to in vitro assay design and optimization and derive actionable biological conclusions and bring new experimental proposals. Possess a thorough knowledge of experimental design and underlying scientific principles related to immune pathways and readouts using primary human, mice, and NHP cells.

· Perform ex-vivo and in-vitro cellular assays with a strong emphasis on flow cytometry and immuno-assays, including ELISA and MSD.

· Independently analyze and interpret multi-parameter data sets and generate high-quality summary reports in a timely manner, and present findings in the inter and intra-departmental group meetings.

· Effective teamwork and engagement with broader team members on general lab activities and rodent tissue processing from in vivo studies.

· Support routine lab and instrument maintenance.


Education and Experience: 

· MS with 6+ years of relevant experience or Ph.D. with 2+ years of relevant experience

· Background in immunology, immuno-oncology, and/or molecular and cellular biology

· Experience in multi-parameter flow cytometry, ELISA, immunological assays, and cell culture and expansion techniques.

· Immunology: 3 years (Preferred) 

· Industry experience (Preferred)

· Excellent record keeping of experimental data and results and maintaining a current and accurate electronic notebook (ELN). 

· Excellent organizational, oral, and written communication skills.


Adaptability: Responds resourcefully, flexibly, and positively when faced with new challenges, transitions, and demands. Willingly and effectively deals with the stress and complexities of various situations. Moves forward productively and optimistically under conditions of change and uncertainty.

Collaboration: Embodies and promotes collaboration and works effectively with others across the organization to achieve goals. Demonstrates proficient cross-company communication, cultural sensitivity, and partnership in interactions with others. Involves others in decisions and plans and credits them for their contributions and accomplishments.

Execution: Drives execution of strategic and operating plans while maintaining operational effectiveness. Conveys a strong sense of urgency around continuous improvement, achieving high-quality results, and accelerating business performance. Addresses problems directly and drives 

changes necessary to achieve business objectives.

Relationship Building: Establishes and maintains strong relationships internally and externally. Respects and relates well to management, colleagues, and peers. Champions a culture of respect, diversity, and inclusion that values and respects individuals. Earns the respect of others through principled leadership, sound business ethics, and authenticity.

Location: Cambridge, MA ( We are located in Lower Cambridge, called Cambridgeport)

When You Join Marengo, You Will Have:

• Free parking, Cambridge location reachable by public transportation (Red Line)

• Customized and competitive health coverage, including medical offered through BCBS (HMO/PPO), dental, and vision

• Flexible Spending Accounts for medical and dependent care expenses

• Eligible from the first day for 401K, no matching

• A robust package of Marengo-paid insurance coverage, including life insurance, short-term and long-term disability

• 20 days of vacation and one personal day per year, in addition to 13 company holidays 

TO ALL AGENCIES: Please, no phone calls or emails to any employee of Marengo about our openings. All resumes submitted by search firms/employment agencies to any employee at Marengo via email, the internet or in any form and/or method will be deemed the sole property of Marengo unless such search firms/employment agencies were engaged by Marengo for this position and a valid agreement with Marengo is in place. In the event a candidate who was submitted outside of the Marengo agency engagement process is hired, no fee or payment of any kind will be paid.

Marengo Therapeutics, Inc. is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service or any other class protected by state or federal law.