Lyra Therapeutics, Inc. is a clinical-stage biotechnology company developing novel, integrated drug and delivery solutions for the localized treatment of patients with chronic rhinosinusitis (CRS) and other chronic diseases. Lyra has two investigational product candidates, LYR-210 and LYR-220, in late-stage development for CRS, a highly prevalent inflammatory disease of the paranasal sinuses which leads to debilitating symptoms and significant morbidities. LYR-210 and LYR-220 are bioresorbable polymeric matrices designed to be administered in a brief, non-invasive, in-office procedure and are intended to deliver up to six months of continuous mometasone furoate drug therapy to the sinonasal passages as an alternative to sinus surgery. LYR-210 is designed for surgically naïve patients and is being evaluated in the ENLIGHTEN Phase 3 clinical program, while LYR-220, an enlarged matrix, is being evaluated in patients who have recurrent symptoms despite surgery in the BEACON Phase 2 clinical trial.  These two product candidates are designed to treat the estimated four million CRS patients in the United States who fail medical management each year.

Our team is growing and we are currently seeking a General Counsel to develop and guide Lyra’s legal strategy. In this critical role, the General Counsel will be responsible for overseeing all legal and compliance matters and will be a key member of the senior leadership team. They will provide strategic legal guidance, manage regulatory compliance, and ensure our business operations align with applicable laws and regulations.

Responsibilities

Corporate Governance and Regulatory Compliance:

• Develop and implement policies and procedures to ensure compliance with applicable laws and regulations, including securities laws, corporate governance guidelines, and industry-specific regulations
• Provide guidance and support to the board of directors, senior management, and other stakeholders on matters related to corporate governance. Act as a trusted advisor, providing expert guidance on legal and compliance matters
• Advise the Board and management on the entire spectrum of legal issues, including regulatory compliance, portfolio strategy, securities regulations, commercialization agreements, risk management, tax implications, government affairs, litigation and investigations, corporate structure, and operational matters

Contract Negotiation and Risk Management:

• Oversee contract management and negotiation, ensuring the company's interests are protected while minimizing legal risks
• Review and negotiate a variety of agreements, including vendor contracts, partnership agreements, and other strategic contracts
• Advise on risk management strategies, identify potential legal exposures, and develop appropriate measures to minimize risks

Legal and Compliance Teams Leadership:

• Collaborate with internal teams to identify potential legal risks and develop strategies for mitigating them effectively
• Develop and execute a legal strategy that aligns with Lyra’s business objectives
• Manage external legal resources as needed

Litigation, Government Investigations, and Compliance:

• Oversee all litigation and legal disputes involving Lyra Therapeutics including managing external counsel, if necessary
• Coordinate responses to government investigations and regulatory inquiries
• Ensure compliance with applicable laws, regulations, and industry standards

• Juris Doctor (JD) degree
• Proven experience (10+ years) as a General Counsel in biotech
• Extensive experience interacting with the Board of Directors and advising senior management on a broad range of legal and compliance issues
• Strong knowledge and expertise in regulatory matters, portfolio strategy, securities regulations, commercialization, risk management, tax, compliance, government affairs, litigation/investigations, corporate structure, and operations
• Demonstrated experience in M&A and BD&L transactions
• Strong budget and financial acumen

At Lyra, we value creativity, leadership, and collaboration.  The company sees significant expansion opportunities for our platform, and look for people who are driven to succeed, innovative, and adaptable.  We offer a competitive compensation and benefit package with opportunities to join a fast-paced, high performing team.  For consideration, please submit cover letter and CV.