BioAge Labs, Inc (BIOA) is a clinical-stage biotechnology company that is harnessing the biology of human aging to develop novel targets and therapies for metabolic diseases.

We are seeking a skilled Research Associate I/II to join our in vivo preclinical team and play a vital role in driving our drug discovery efforts.

The Role: In this position, you will apply your technical expertise in rodent models to independently conduct key measurements for in vivo studies, generate critical data to evaluate our lead therapeutic candidates and advance our programs, and ensure the ethical treatment of research animals. This is a full-time, on-site position based in Richmond, CA (Moving in Q1'25 to Emeryville)

You: You have robust animal handling abilities and experimental skills honed through deep experience working with laboratory mice. Your motivation and organizational skills allow you to manage multiple studies simultaneously in a fast-paced environment. You are a team player excited to expand your scientific skills while contributing to groundbreaking therapies targeting aging-related diseases.

Essential Job Duties:

• Independently perform dosing, blood collection, measurement, and clinical observation of laboratory mice to support in vivo studies.
• Gain proficiency in or possess proficiency in-vivo technical skills, including dosing (IP/IV/PO/SC/IM/IT/IN), bleeding (submandibular/ submental/retro-orbital/tail vein/cardiac), euthanasia, and necropsy of laboratory mice.
• Under minimal supervision, manage pre-study preparations for mice, such as shaving and animal identification (e.g., ear tag, ear notching, tail mark)
• Collect and record relevant data, providing feedback to team members on the progress of assigned projects.
• Maintain detailed records of measurements, observations, and other required data.
• Adhere to animal welfare rules and regulations under supervision.
• Monitor the health of laboratory mice, recognizing signs of disease and adhering to humane endpoints.
• Participate in weekend and holiday rotations with peers.
• Take part in vivarium maintenance, including restocking supplies, cleaning, and husbandry duties.
• Help prepare and maintain laboratory equipment and supplies, ensuring inventory management.
• Work collaboratively towards the goals of our therapeutic programs and may provide guidance to junior team members.
• Train in advanced procedures and techniques as necessary.

Required Skills and Abilities:

• Hands-on in-vivo technical skills.
• Strong motivation and the ability to multitask and meet deadlines in a dynamic environment.
• Organized and disciplined in record-keeping.
• Effective communication skills, both verbal and written.
• Skilled in IM, IV, IP, PO, SC dosing, and proficient in various blood collection methods (preferred).
• Prior experience in reviewing and analyzing data from studies, including study design and management.
• Familiarity with laboratory practices and equipment.
• Some understanding of aging and/or age-related diseases in animal models is beneficial.

Education and Qualifications:

• Bachelor’s degree in Biology or a related discipline with 1 or more years of experience preferred, or 2 to 5 years of hands-on experience with laboratory rodents.
• Pursuit or possession of AALAS certification (ALAT, LAT, LATG) is desirable.

Our Company

BioAge Labs, Inc (BIOA) is a clinical-stage biopharmaceutical company developing therapeutic product candidates for metabolic diseases, such as obesity, by targeting the biology of human aging. BioAge’s lead product candidate, azelaprag, is an orally available small molecule agonist of APJ that was observed to promote metabolism and prevent muscle atrophy on bed rest in a Phase 1b clinical trial. In mid-2024, BioAge initiated a Phase 2 trial of azelaprag in combination with tirzepatide for the treatment of obesity in older adults. Azelaprag has potential as an oral regimen to amplify weight loss and improve body composition in patients on obesity therapy with incretin drugs. BioAge is also developing orally available small molecule brain penetrant NLRP3 inhibitors for the treatment of diseases driven by neuroinflammation. BioAge’s preclinical programs, based on novel insights from the company’s discovery platform built on human longevity data, address key pathways in metabolic aging.

Our Workplace

BioAge offers competitive salary, a comprehensive compensation package, and generous paid time off in addition to company-observed holidays. We provide comprehensive health and wellness benefits (medical, dental, and vision insurance) and a 401(k) retirement savings plan with matching employer contributions, and we support families through childcare and fertility benefits. We also pride ourselves in giving employees many opportunities for career development, including a generous annual budget for continued learning and a dedication to training and skill development. The salary for this role is expected to be approximately $65,000 - $80,000, depending whether offered a role as Research Associate I or II. We are open to the concept that different experience levels add value to the team in different ways, and therefore will consider a variety of experience and offer commensurate pay.

At BioAge, we embrace diversity and differences while we learn from each other, and we believe that every team member has an important role to play. We are an equal opportunity employer. BioAge prohibits discrimination and harassment of any type and affords equal employment opportunities to employees and applicants without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law. BioAge conforms to the spirit as well as to the letter of all applicable laws and regulations.