Codiak is driven by a belief that the most innovative medicines are found at the intersections of scientific fields and that problem-solving across disciplinary boundaries is necessary to be a leader in bionanoparticle therapeutics. The Downstream Processing group at Codiak is seeking a talented, creative, and passionate candidate motivated to bring impactful therapeutic modalities to patients with unmet medical needs. The group prides itself on integrity and collaboration while almost always finding time to have fun at work.
The Scientist will develop and optimize the company’s novel exogenous exosome/synthetic nucleic acid loading platform. The successful candidate will be highly motivated, thrive on increasing levels of responsibility, and have a demonstrated capability to drive science in a fast-paced environment. Responsibilities will include providing technical/scientific expertise and leadership in all areas of drug process development such as loading, cleanup, filtration, and formulation. Additional responsibilities will include assisting in the development of processes for the purification of exosomes.
Ph.D. in chemistry, polymer chemistry, biochemical engineering or similar disciplines with a minimum of 2 years related experience; expert knowledge of scientific principles and concepts;
A. Proficient in organic, polymer, and bioconjugation chemistry;
B. Experience developing processes with exosomes, liposomes, and/or lipid nanoparticles;
C. Background in applying advanced technologies to develop methods for loading of payloads into and onto nanoparticles;
D. Experience in development and transfer of production processes for nanoparticles to cGMP manufacturing organizations;
E. Demonstrated technical proficiency, work ethic, scientific creativity, collaboration with others and independent thought;
F. Excellent communication and presentation skills (oral and written);
G. Reputation as emerging leader in field with sustained performance and accomplishment