Molecular Pharmacology Co-op (July to December)

Do you have the passion to join a group whose mission is to pioneer the discovery of a new class of medicines to treat diseases unaddressed by today’s therapies? Does it excite you to be a part of a company with a platform that can address any disease area with high unmet medical need? If yes, you may be a great fit to join Arrakis on our path to bring powerful new RNA-targeted small molecule (rSM) medicines to millions of patients.

Your Impact at Arrakis

The mission of Arrakis Therapeutics is to extend small molecule medicines into new realms of biology by discovering and developing compounds that selectively target RNA. By targeting distinct RNA structure: function relationships, Arrakis aims to generate drug candidates with novel mechanisms of action for molecular targets that are challenging to drug with other approaches, opening up vast new realms of human biology for medicine.

The successful individual is a team player who possesses a sense of personal warmth that is welcoming and comfortable and can build trust and credibility with team members. This person must be exceedingly well organized, flexible, and enjoy the challenges of working with a team of diverse individuals. 

This co-op will not only gain experience in a scaling biotech company, but they will also learn various skills for operating and maintaining a state-of-the-art HPLC-mass spectrometer for use in identification and quantification of small molecules. Co-op will also learn the principles of mass spectrometry and chromatographic separation of small molecules and small molecule / RNA complexes. All these skills will further equip this co-op for a broad range of demands in future industry settings. 

This co-op starts on July 10 and ends on December 15, 2023. Some start/end date flexibility is possible.

Key tasks and responsibilities include, but are not limited to:

  • Assist with the design of, and execution of, a project that will provide insight into whether our HPLC-MS-based screening activities can be further improved in a specific dimension. 
  • Learn about and train on routine screening data generation workflows based on HPLC-MS, that are used internally at Arrakis.
  • Function independently and in team setting to design, conduct, and analyze experimental data. 
  • Record, communicate, and present experimental outcomes effectively across the organization, and maintain electronic records on these outcomes.
  • Present to a wide audience on this project at the completion of their internship period. 
  • Bachelor’s degree or current participation in a bachelor’s degree program in a major related to the position, such as Chemistry, Biochemistry, Biotechnology, e.g., or similar, is preferred. Other educational qualifications and related work experience to be considered.
  • Experience working with HPLC and/or Mass spectrometry instrumentation is a plus but not required.
  • Some experience with more general laboratory instrumentation and automation is desired. 
  • Some experience with liquid handling devices is desired.
  • Organized and detailed oriented.
  • Work cross functionally with multiple different functions.
  • Strong communication skills.
  • Exhibits passion and excitement over work. 
  • Adjusts quickly to changing priorities and conditions and copes effectively with complexity and change.

Interested in learning more about Arrakis? Click on the links below!

Arrakis/Amgen Partnership (Jan. 2022)

Arrakis/Roche Alliance Partnership (Apr. 2021)

Dark Matter Blog: Arrakis achieves escape velocity 

Dark Matter Blog: Following our pole star 

Arrakis is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, national origin or ancestry, sex, pregnancy, sexual orientation, gender identity, age, disability, military service, veteran status, genetic information, or any other characteristic protected by law.