The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with developmental brain disorders. We are one of the only research institutions in the world focused specifically on understanding how genes and the environment influence the way our brains develop that lead to conditions such as schizophrenia, autism, bipolar disorder and related developmental brain disorders. Through our cutting-edge research, answers are emerging and being translated into a robust pipeline of new drugs in development. And, by focusing on genes and their dynamic interplay with the environment, we are getting even closer to the “holy grail” in medical research, the discovery of strategies for primary prevention.
We are a group of dedicated, multidisciplinary and optimistic researchers, working at the cutting edge of science, utilizing state-of-the-art tools to unlock the mystery of the brain and transform the way we approach the development of new treatments, and ultimately cures. LIBD is an independent 501(c)(3) medical research institute located in the Bioscience Park on the campus of the Johns Hopkins School of Medicine and Hospital in Baltimore, MD.
A Research Associate position is available within Drug Discovery and Development Group of the Lieber Institute for Brain Development. The Drug Discovery and Development Group is a multidisciplinary team of medicinal chemists, biochemists, and neuroscientists focused on identifying and validating novel therapeutics for the treatment of schizophrenia and related disorders. The successful candidate will work within the In Vivo Pharmacology lab. The two main goals of the In Vivo Pharmacology group are:
1) Elucidate the neurobiological substrates underlying the development and progression of schizophrenia and related disorders in order to identify potential therapeutic targets
2) Characterize the pharmacokinetic/pharmacodynamic (PK/PD) relationship of novel compounds in relevant model systems.
1) Design and conduct primary in vivo pharmacological assays utilized by the group including:
a) Touchscreen-based mouse behavioral assays
b) Neurochemical biomarker identification and validation studies
2) Design and write study protocols and standard operating procedures (SOPs)
3) Assist in the maintenance of the Drug Discovery and Development Group animal colony
4) Produce high-quality reports and presentations for internal and external collaborators
• BS degree in related field is required. Master’s degree preferred.
• At least 3 years of full-time laboratory research experience is required.
• A strong background in neuroscience, pharmacology, molecular biology, or a related field Proficiency with rodent models of behavior.
• Proficiency in drug administration techniques including intraperitoneal injection and oral gavage.
To Apply: Interested applicants should submit a cover letter and resume with the subject line “Research Associate – Drug Discovery”.
- Remaining in a seated or standing position for extended periods of time;
- Reaching and grasping to manipulate objects with fingers;
- Mobility, including the ability to maneuver around a laboratory setting including the ability to move materials weighing up to 25 pounds;
- Communication skills using the spoken and written word;
- Having the ability to receive detailed information through oral communication;
- All other physical demands in a standard laboratory environment.
** If accommodations are needed due to pregnancy or a disability, please contact email@example.com
EEOC Statement: At the Lieber Institute, we are committed to a work environment of mutual respect where employment decisions are based on merit. As an equal opportunity employer, the Lieber Institute does not discriminate in employment opportunities on the basis of race, color, religion, color, sex, gender identity/expression, sexual orientation, pregnancy, marital status, age, national origin or ancestry, citizenship, disability (physical or mental), genetic information, military service, or other non-merit based factors protected by state or federal law or local ordinance, with regard to any position or employment for which the applicant or employee is qualified.