The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with developmental brain disorders. We are one of the only research institutions in the world focused specifically on understanding how genes and the environment influence the way our brains develop that lead to conditions such as schizophrenia, autism, bipolar disorder and related developmental brain disorders. Through our cutting-edge research, answers are emerging and being translated into a robust pipeline of new drugs in development. And, by focusing on genes and their dynamic interplay with the environment, we are getting even closer to the “holy grail” in medical research, the discovery of strategies for primary prevention.
We are a group of dedicated, multidisciplinary and optimistic researchers, working at the cutting edge of science, utilizing state-of-the-art tools to unlock the mystery of the brain and transform the way we approach the development of new treatments, and ultimately cures. LIBD is an independent 501(c)(3) medical research institute located in the Bioscience Park on the campus of the Johns Hopkins School of Medicine and Hospital in Baltimore, MD.
The Lieber Institute for Brain Development is home to a repository of >3000 postmortem human brain subjects spanning all diagnoses across the lifespan. A critical brain research challenge lies in identifying molecular mechanisms of disease and aging at the cell-type level within specific brain regions. We employ the laser capture microdissection (LCM) system to isolate specific cell populations from frozen postmortem human brain tissue, and perform comparative molecular characterizations of these cells between control and diseased samples. The position reports to the Chief Medical Officer and Staff Scientist of Neuropathology.
This position will involve training in multiple disciplines including human brain neuroanatomy, specific neuron morphology, cryostat sectioning, laser capture microdissection, RNA and protein extraction and group data science analysis in the context of scientific research questions. The candidate will be expected to contribute to scientific publications and develop molecular cell type assays for grants and contracts.
Education: BA/BS degree in Neuroscience or related field is required. MS is preferred
Experience: a minimum of 3 years’ experience with molecular biology techniques is required
Knowledge, Skills and Abilities:
• A track record of former scientific publications and / or research thesis completion is a plus.
• A basic understanding and demonstrable experience with wet lab techniques (e.g. DNA, RNA, protein isolation protocols) and scientific methodology is required. Knowledge/experience with microscopy techniques, cellular morphology and basic neuroanatomy is a plus.
• Good laboratory practice track record is a must (e.g. patience with scientific methodology standardization, maintaining a detailed project workbook, basic operations and management skills including inventory/ordering materials/interfacing with different scientific groups/project deliverable deadlines, etc. is critical for success in this position).
• Ability to work independently or with minimal supervision post-training is required.
To Apply: Interested applicants should submit a cover letter and resume with the subject line “Research Associate – Neuropathology”.
- Remaining in a seated or standing position for extended periods of time;
- Reaching and grasping to manipulate objects with fingers;
- Mobility, including the ability to maneuver around a laboratory setting including the ability to move materials weighing up to 25 pounds;
- Communication skills using the spoken and written word;
- Having the ability to receive detailed information through oral communication;
- All other physical demands in a standard laboratory environment.
** If accommodations are needed due to pregnancy or a disability, please contact email@example.com
EEOC Statement: At the Lieber Institute, we are committed to a work environment of mutual respect where employment decisions are based on merit. As an equal opportunity employer, the Lieber Institute does not discriminate in employment opportunities on the basis of race, color, religion, color, sex, gender identity/expression, sexual orientation, pregnancy, marital status, age, national origin or ancestry, citizenship, disability (physical or mental), genetic information, military service, or other non-merit based factors protected by state or federal law or local ordinance, with regard to any position or employment for which the applicant or employee is qualified.