A little about us:
The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with developmental brain disorders. We are one of the only research institutions in the world focused specifically on understanding how genes and the environment influence the way our brains develop that lead to conditions such as schizophrenia, autism, bipolar disorder and related developmental brain disorders. Through our cutting-edge research, answers are emerging and being translated into a robust pipeline of new drugs in development. And, by focusing on genes and their dynamic interplay with the environment, we are getting even closer to the “holy grail” in medical research, the discovery of strategies for primary prevention.
We are a group of dedicated, multidisciplinary and optimistic researchers, working at the cutting edge of science, utilizing state-of-the-art tools to unlock the mystery of the brain and transform the way we approach the development of new treatments, and ultimately cures. LIBD is an independent 501(c)(3) medical research institute located in the Bioscience Park on the campus of the Johns Hopkins School of Medicine and Hospital in Baltimore, MD.
We are seeking a self-motivated individual to join our research group as a Research Associate. This position is open to bench laboratory scientists seeking experience in a translational research setting with a focus on spatial transcriptomics projects in postmortem human brain tissue in a dynamic team-based environment. Projects aim to generate transcriptome-scale maps in the human brain to understand differences in spatial gene expression in neuropsychiatric disorders. Previous bench experience in molecular/cellular biology, confocal microscopy, FACS sorting, and/or next generation sequencing is required. The position requires ability to participate in experimental design, conduct experiments and work with computational biologists to analyze data. Initiative to learn new methods and perform work efficiently and carefully are essential.
· RNA-seq library construction
· Nuclei isolation and FACs sorting
· RNA isolation, quantitative-PCR
· Confocal imaging and slide-scanning
· Assist with brain tissue dissections
· Other duties as assigned
EEOC Statement: At the Lieber Institute, we are committed to a work environment of mutual respect where employment decisions are based on merit. As an equal opportunity employer, the Lieber Institute does not discriminate in employment opportunities on the basis of race, color, religion, color, sex, gender identity/expression, sexual orientation, pregnancy, marital status, age, national origin or ancestry, citizenship, disability (physical or mental), genetic information, military service, or other non-merit based factors protected by state or federal law or local ordinance, with regard to any position or employment for which the applicant or employee is qualified.
· Bachelor’s degree in neuroscience, molecular or cellular biology or a closely related field is required. MS preferred.
· Three years or more of laboratory research experience is required.
· Excellent organizational and communication skills
Special Knowledge, Skills, and Abilities:
Familiarity with the following techniques is a plus:
· Single-cell sequencing platforms
· Human neuroanatomy
· Single cell RNA-sequencing
· Confocal Microscopy
· Image processing analysis in Python and/or Matlab
· Gene expression analysis in R/Bioconductor
- Remaining in a seated or standing position for extended periods of time;
- Reaching and grasping to manipulate objects with fingers;
- Mobility, including the ability to maneuver around a laboratory setting including the ability to move materials weighing up to 25 pounds;
- Communication skills using the spoken and written word;
- Having the ability to receive detailed information through oral communication;
- All other physical demands in a standard laboratory environment.
** If accommodations are needed due to pregnancy or a disability, please contact firstname.lastname@example.org