A little about us:
The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with developmental brain disorders. We are one of the only research institutions in the world focused specifically on understanding how genes and the environment influence the way our brains develop that lead to conditions such as schizophrenia, autism, bipolar disorder and related developmental brain disorders. Through our cutting-edge research, answers are emerging and being translated into a robust pipeline of new drugs in development. And, by focusing on genes and their dynamic interplay with the environment, we are getting even closer to the “holy grail” in medical research, the discovery of strategies for primary prevention.
We are a group of dedicated, multidisciplinary and optimistic researchers, working at the cutting edge of science, utilizing state-of-the-art tools to unlock the mystery of the brain and transform the way we approach the development of new treatments, and ultimately cures. LIBD is an independent 501(c)(3) medical research institute located in the Bioscience Park on the campus of the Johns Hopkins School of Medicine and Hospital in Baltimore, MD.
We are seeking a talented and motivated scientist to join the Drug Discovery team at the Lieber Institute as a Staff Scientist to help in our efforts to discover transformative new therapies for patients in need. This position will work very closely with faculty in the Johns Hopkins Pharmacology Department as well as with chemists, biologists, and data scientists to plan and execute experiments designed to identify and validate new therapeutic strategies to treat schizophrenia and related developmental brain disorders and develop innovative drug discovery strategies.
The ideal candidate will have a background in molecular and cellular biology, as well as target identification and validation, with a strong track record of collaboration across disciplines. Experience with knockdown or over-expression techniques in in vitro models including CRISPR, shRNA, ASO or lentiviral overexpression to define gene expression programs and inflammatory pathways, including the development and implementation of novel methods is a plus. Expertise in HPLC techniques, mass spectrometry analysis, immunoprecipitation techniques, protein purification from bacterial cultures and cell lines desirable. Experience in blood and serum-based biomarkers and peripheral blood mononuclear cell analyses would be a plus.
EEOC Statement: At the Lieber Institute, we are committed to a work environment of mutual respect where employment decisions are based on merit. As an equal opportunity employer, the Lieber Institute does not discriminate in employment opportunities on the basis of race, color, religion, color, sex, gender identity/expression, sexual orientation, pregnancy, marital status, age, national origin or ancestry, citizenship, disability (physical or mental), genetic information, military service, or other non-merit based factors protected by state or federal law or local ordinance, with regard to any position or employment for which the applicant or employee is qualified.
Special Knowledge, Skills, and Abilities:
Physical Requirements:- Remaining in a seated or standing position for extended periods of time;- Reaching and grasping to manipulate objects with fingers;- Mobility, including the ability to maneuver around a laboratory setting including the ability to move materials weighing up to 25 pounds;- Communication skills using the spoken and written word; - Having the ability to receive detailed information through oral communication;- All other physical demands in a standard laboratory environment.
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