Research Assistant- Molecular Neuroanatomy
Description

  

A little about us:


The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with developmental brain disorders. We are one of the only research institutions in the world focused specifically on understanding how genes and the environment influence the way our brains develop that lead to conditions such as schizophrenia, autism, bipolar disorder and related developmental brain disorders. Through our cutting-edge research, answers are emerging and being translated into a robust pipeline of new drugs in development. And, by focusing on genes and their dynamic interplay with the environment, we are getting even closer to the “holy grail” in medical research, the discovery of strategies for primary prevention.


We are a group of dedicated, multidisciplinary and optimistic researchers, working at the cutting edge of science, utilizing state-of-the-art tools to unlock the mystery of the brain and transform the way we approach the development of new treatments, and ultimately cures. LIBD is an independent 501(c)(3) medical research institute located in the Bioscience Park on the campus of the Johns Hopkins School of Medicine and Hospital in Baltimore, MD.


Job Summary: 


We are seeking an enthusiastic and self-motivated research assistant with experience in neuroscience and molecular neurobiology to join our interdisciplinary research team at the Lieber Institute for Brain Development. This position is open to bench laboratory scientists seeking a position within a translational research setting with a focus on next generation sequencing projects using 10x Genomics single cell gene expression technology in postmortem human brain tissue. The successful applicant will work in collaboration with a team of scientists to create cell type-specific reference profiles in human brain regions important for addiction and neuropsychiatric disorders. 


Candidates should have training in neuroscience and previous bench experience in molecular/cellular biology, flow cytometry, histological staining, and/or fluorescence microscopy. Responsibilities will include executing experimental protocols independently, analyzing data, as well as communicating scientific findings through presentations and publications. While exceptional wet lab skills are required for this position, computational experience or familiarity with computing in R, MATLAB, or Python is a plus. Initiative to learn new methods and perform work efficiently and carefully are essential.


Overview of Duties: 

  • RNA extraction and qPCR
  • Cryosectioning, histological or immunofluorescence staining, confocal microscopy
  • Single nucleus RNA-sequencing
  • Flow sorting of postmortem human brain nuclei 
Requirements

  

Minimum Qualifications 

  • BA or BS in Neuroscience, Cell Biology, or a closely related field
  • Molecular biology experience
  • Excellent organizational and communication skills
  • Flexible work schedule 

Familiarity with any of the following topics or techniques is a plus:

  • Programming in MATLAB, R or Python
  • Flow cytometry
  • Next generation sequencing
  • Neuroanatomy

** If accommodations are needed due to pregnancy or a disability, please contact jobs@libd.org 


EEOC Statement: At the Lieber Institute, we are committed to a work environment of mutual respect where employment decisions are based on merit. As an equal opportunity employer, the Lieber Institute does not discriminate in employment opportunities on the basis of race, color, religion, color, sex, gender identity/expression, sexual orientation, pregnancy, marital status, age, national origin or ancestry, citizenship, disability (physical or mental), genetic information, military service, or other non-merit based factors protected by state or federal law or local ordinance, with regard to any position or employment for which the applicant or employee is qualified.