Senior/Principal Data Engineer, Research Informatics
Waltham, MA Computational Biology
Job Type

Do you have the passion to join a group whose mission is to pioneer the discovery of a new class of medicines to treat diseases unaddressed by today’s therapies? Does it excite you to be a part of a company with a focus on cancer and genetically-validated targets in other disease areas with unmet medical need?  If yes, you may be a great fit to join Arrakis on our path to bring powerful new therapies to millions of patients.

Your Impact at Arrakis

The mission of Arrakis Therapeutics is to extend small molecule medicines into new realms of biology by discovering and developing compounds that selectively target RNA (“rSM”). By targeting distinct RNA structure/function relationships, Arrakis is generating drug candidates with novel mechanisms of action for molecular targets that are challenging to drug in disease areas with high unmet medical need. Identifying functional elements of the transcriptome that can be targeted by rSM’s and establishing mechanism of action requires integrating data across multiple sources.

This role will lead efforts in research informatics to capture and integrating data from various types of internal chemical and biological data sets. Leveraging your expertise in data management, you will implement technical solutions to transition our data platform into a robust, scalable, and integrated system. The ideal candidate will enjoy working in a collaborative, fast-paced start-up environment, leveraging a high degree of scientific rigor, creativity and innovation.

Job Responsibilities

  • Collaborate with teams across the company to design, develop, implement, and maintain data structures within a relational database
  • Develop data flow pipelines to extract, transform, and load (ETL) data from various sources and deploy these customized ETL pipelines 
  • Develop and deploy web-based interfaces to that allow scientist to access and visualize data
  • Provide training to scientist in the design, use, and implementation of custom data systems
  • Work effectively in a cross-functional capacity with the platform biology, target biology, and medicinal chemistry teams to develop data solutions for addressing business and scientific needs through-out the company
  • Effectively communicate proposals, analyses, and project goals

Interested in learning more about Arrakis? Click on the links below!

Dark Matter Blog: Arrakis achieves escape velocity 

Dark Matter Blog: Following our pole star

Arrakis/Roche Alliance Partnership

Arrakis is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, national origin or ancestry, sex, pregnancy, sexual orientation, gender identity, age, disability, military service, veteran status, genetic information, or any other characteristic protected by law.

  • B.A. or B.S. in Computational Science, Applied mathematics, Life sciences, or related field
  • 5+ years of relevant industry experience required
  • Extensive expertise in common programing and scripting languages (python, R,  C++, etc.) with a solid understanding of data structures and algorithms
  • Extensive Experience with relational databases development and management (Postgres, MySQL, etc.)
  • Experience working in a DevOps or data engineer role using cloud-based infrastructure (AWS, GCP, or MS Azure)
  • Experience writing, testing, and maintaining version-controlled software
  • Adjusts quickly to changing priorities and conditions and copes effectively with complexity and change