Postdoctoral Fellow – Functional Genomics


A little about us:

The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with developmental brain disorders. We are one of the only research institutions in the world focused specifically on understanding how genes and the environment influence the way our brains develop that lead to conditions such as schizophrenia, autism, bipolar disorder and related developmental brain disorders. Through our cutting-edge research, answers are emerging and being translated into a robust pipeline of new drugs in development. And, by focusing on genes and their dynamic interplay with the environment, we are getting even closer to the “holy grail” in medical research, the discovery of strategies for primary prevention.

We are a group of dedicated, multidisciplinary and optimistic researchers, working at the cutting edge of science, utilizing state-of-the-art tools to unlock the mystery of the brain and transform the way we approach the development of new treatments, and ultimately cures. LIBD is an independent 501(c)(3) medical research institute located in the Bioscience Park on the campus of the Johns Hopkins School of Medicine and Hospital in Baltimore, MD.

Job Summary: 

The McConnell Lab at the Lieber Institute for Brain Development is recruiting a Postdoctoral Fellow / Research Scientist in human single cell genomics. This position involves using human induced pluripotent stem cell culture and brain organoid derivation to study schizophrenia and movement disorders. Proficiency in biochemical assays, molecular biology, brain histology, and fluorescence microscopy are required. Additional experience with electrophysiological phenotyping using multi-electrode arrays and/or with 10X single cell sequencing library preparation are also valued. Moreover, the ideal candidate will have some experience with Python or R computational packages and a strong interest in learning single cell analysis. The scientist will be committed to a common mission, a team effort, and collaborations across academia and industry. 



Minimum Qualifications:

· PhD in Neuroscience, Cell Biology, or related discipline.

· At least 2 years experience with cell culture and biochemistry, experience with hiPSC culture is preferred.

· Excellent time management and problem-solving skills.

· Excellent written and verbal communication skills, including proficiency with Excel, Word, Powerpoint, Photoshop and related software.

Special Knowledge, Skills, and Abilities:

· Proficiency in biochemical assays, molecular biology, brain histology, and fluorescence microscopy are required

Experience with the following topics or techniques is beneficial:

· Electrophysiological phenotyping

· Multi-electrode arrays

· 10X single cell sequencing library preparation

· Python or R computational packages

Physical Requirements:

- Remaining in a seated or standing position for extended periods of time;

- Reaching and grasping to manipulate objects with fingers;

- Mobility, including the ability to maneuver around a laboratory setting including the ability to move materials weighing up to 25 pounds;

- Communication skills using the spoken and written word; 

- Having the ability to receive detailed information through oral communication;

- All other physical demands in a standard laboratory environment.

** If accommodations are needed due to pregnancy or a disability, please contact 

EEOC Statement: At the Lieber Institute, we are committed to a work environment of mutual respect where employment decisions are based on merit. As an equal opportunity employer, the Lieber Institute does not discriminate in employment opportunities on the basis of race, color, religion, color, sex, gender identity/expression, sexual orientation, pregnancy, marital status, age, national origin or ancestry, citizenship, disability (physical or mental), genetic information, military service, or other non-merit based factors protected by state or federal law or local ordinance, with regard to any position or employment for which the applicant or employee is qualified.