The Analytical Scientist I in the Analytical Team is responsible for independently performing routine and advanced analytical testing to support the development of particulate-based drug delivery systems. Strong liquid chromatography (LC) expertise is required for this role, and this hire is intended to add an additional LC expert to the Analytical Team. This role involves conducting advanced analyses using LC (e.g., HPLC/UPLC) and CE for nucleic acid, API, and lipids, as well as dissolution/in vitro release testing. The Analytical Scientist I will assist in method development and qualification activities (with an emphasis on LC methods), provide instrument training for junior staff, and participate in analytical problem-solving and troubleshooting. The Analytical Scientist will work independently and collaboratively across multiple departments to support multiple projects in parallel, ensuring the timely and organized completion of project objectives.
Job Description:
Role and Responsibilities
1. Analytical Testing:
§ Independently perform routine analytical testing and advanced analysis with minimal direction.
§ Conduct advanced analyses using liquid chromatography (LC; e.g., HPLC/UPLC) as a core technique, along with CE, for nucleic acid, API, and lipids, as well as dissolution/in vitro release testing.
§ Apply strong LC expertise to independently run, troubleshoot, and interpret LC analyses, and serve as an LC resource for the team.
2. Instrument Training and Operation:
§ Assist in training junior staff on instrument operation and analytical techniques, including LC.
§ Demonstrate knowledge of instrument operation and maintenance, including LC systems.
3. Method Development and Qualification:
§ Assist in the development and qualification of analytical methods, with an emphasis on LC methods, to ensure accuracy and reliability of results.
4. Problem Solving and Troubleshooting:
§ Participate in analytical problem-solving and troubleshooting activities, including LC method and instrument troubleshooting, to improve laboratory processes and outcomes.
5. Data Analysis and reporting:
§ Analyze and report data from routine assays and development activities.
§ Present data internally to team members and stakeholders.
6. Documentation and review:
§ Maintain lab notebooks with detailed and accurate records of experiments and results.
§ Review technical documents such as Standard Operating Procedures (SOPs), methods, and reports for accuracy and compliance.
7. Study Design
§ Assist in the design of in vitro release and stability studies to support product development.
8. EH&S Practices:
§ Adhere to Environmental Health & Safety (EH&S) practices and protocols to maintain a safe working environment.
Preferred Skills
- Advanced LC expertise, including method development and qualification for particulate drug delivery formulations
- Experience with complex analytical testing and data analysis
- Familiarity with laboratory safety protocols and EH&S practices.
Supervisory responsibilities
N/A
Additional Notes
- This position requires working in a laboratory environment with potential exposure to chemicals
- The role may involve standing for extended periods and performing repetitive tasks.
- This role may involve working outside standard office hours (9.00-5.30 pm) occasionally to meet project needs.
Qualifications and Education Requirements
- Bachelor’s degree in chemistry, pharmacy, or pharmaceutical sciences with 2- 5 years of experience, or a master’s degree with 0 – 1 years of experience.
- Demonstrated hands-on expertise in liquid chromatography (e.g., HPLC/UPLC), including method execution, data interpretation, and troubleshooting.
- Proficient in Microsoft Office (Word, Excel, PowerPoint).
- Strong Analytical and problem-solving skills
- Excellent attention to detail and organization skills
- Ability to work independently and as part of a team
- Excellent verbal and written communication skills and ability to collaborate cross-functionally.